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Komórki beta trzustki

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Zamknięte w odpowiednich osłonkach komórki świńskiej trzustki, produkujące insulinę, przez dziewięć miesięcy chroniły pawiana przed cukrzycą. To sukces uczonych z kalifornijskiego Duke University.

Komórki beta trzustki, tworzące w niej tak zwane wysepki Langerhansa, wydzielają insulinę - hormon wpływający na przemianę węglowodanową, białkową i tłuszczową. Nieprawidłowe działanie wysepek trzustki prowadzi do cukrzycy typu I - we krwi i moczu chorego glukoza osiąga szkodliwy dla zdrowia wysoki poziom. Nieleczona cukrzyca prowadzi między innymi do niewydolności nerek, chorób serca, uszkodzenia nerwów i ślepoty. Dlatego chorzy na cukrzycę typu I muszą przez całe życie wstrzykiwać sobie insulinę. Istnieje też - występująca głównie w starszym wieku - cukrzyca typu II, w której dochodzi do oporności tkanek na insulinę - wprawdzie jest wydzielana, ale nie wywiera efektu.nicorix skład

Od dawna próbuje się ułatwić życie diabetykom. Nie udało się, jak dotąd, skonstruować wszczepianej pod skórę pompy, która podawałaby tyle insuliny, ile trzeba. Powodem jest zbyt mała trwałość mierzących poziom glukozy we krwi czujników. Przeszczep trzustki wymaga odpowiedniego dawcy, a ponadto chory musi przyjmować substancje chroniące przed odrzuceniem obcej tkanki. Rozwiązaniem może być zamknięcie komórek w kapsułkach o porowatych ściankach. Ściany takich kapsułek przepuszczają glukozę i insulinę, ale oddzielają komórki od układu odpornościowego. Próby z nimi trwają od dawna, ale dotąd wyniki nie były zbyt obiecujące.eracto dawkowanie

Wygląda na to, że sukces odnieśli naukowcy z Duke University. Uczeni otoczyli komórki, pobrane ze świńskiej trzustki warstwą złożonego węglowodanu - alginatem i wstrzyknęli tak otrzymane kapsułki do jamy brzusznej chorego na cukrzycę pawiana. Komórki przeżyły i reagowały na poziom glukozy we krwi jak prawdziwa trzustka - wydzielały insulinę, która obniżała poziom glukozy we krwi, gdy było jej za dużo. Funkcjonują bardzo dobrze już od ponad dziewięciu miesięcy. Jeśli kolejne eksperymenty również dadzą pozytywny efekt, niebawem powinny się rozpocząć na ludziach. psorilax krem apteka

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